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  • Title: Vaccine-preventable pediatric postmeningitic sensorineural hearing loss in southern India.
    Author: Cherukupally SR, Eavey R.
    Journal: Otolaryngol Head Neck Surg; 2004 Mar; 130(3):339-43. PubMed ID: 15054376.
    Abstract:
    OBJECTIVE: The study goal was to assess vaccine-preventable pediatric postmeningitic sensorineural hearing loss in southern India. STUDY DESIGN AND SETTING: We conducted a prospective pilot study from January through March 2001 in a tertiary pediatric hospital in southern India. RESULTS: Sixty-five patients were studied. Thirty-five (54%) patients had positive cerebrospinal fluid cultures, with the most common organisms being Streptococcus pneumoniae and Haemophilus influenzae. An additional 10 (15%) patients were diagnosed with tuberculous meningitis. Of 28 patients who could comply with audiometric evaluations, 8 (28%) had sensorineural hearing loss. CONCLUSIONS: The etiologic organisms of bacterial meningitis in this study population are similar to those organisms in the developed world, with the minority exception of tuberculous meningitis. Further, a similar prevalence of postmeningitic sensorineural hearing loss occurred. SIGNIFICANCE: An effective vaccination program against S. pneumoniae and H. influenzae type b should reduce the prevalence of sensorineural hearing loss due to bacterial meningitis in developing countries with similar bacterial profiles.
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