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Title: From road rash to top allergen in a flash: bacitracin. Author: Jacob SE, James WD. Journal: Dermatol Surg; 2004 Apr; 30(4 Pt 1):521-4. PubMed ID: 15056142. Abstract: BACKGROUND: Bacitracin is an antibiotic that is produced by Bacillus subtilis, which is used in several types of consumer products, including cosmetics and ophthalmic and cutaneous ointments. OBJECTIVE: To call attention to the rising allergic contact dermatitis associated with bacitracin. RESULTS: Mass usage has resulted in an increasing number of clinically relevant allergic contact dermatitis reactions and near fatal anaphylaxis. The North American Contact Dermatitis Group has recorded its emergence as a leading allergen and continues to monitor the ever-growing allergic reaction rates. CONCLUSION: The clinical impact, scientific evidence, and need for medical cost containment all advocate the discontinuation of routine usage of bacitracin in clean surgical wounds.[Abstract] [Full Text] [Related] [New Search]