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  • Title: From road rash to top allergen in a flash: bacitracin.
    Author: Jacob SE, James WD.
    Journal: Dermatol Surg; 2004 Apr; 30(4 Pt 1):521-4. PubMed ID: 15056142.
    Abstract:
    BACKGROUND: Bacitracin is an antibiotic that is produced by Bacillus subtilis, which is used in several types of consumer products, including cosmetics and ophthalmic and cutaneous ointments. OBJECTIVE: To call attention to the rising allergic contact dermatitis associated with bacitracin. RESULTS: Mass usage has resulted in an increasing number of clinically relevant allergic contact dermatitis reactions and near fatal anaphylaxis. The North American Contact Dermatitis Group has recorded its emergence as a leading allergen and continues to monitor the ever-growing allergic reaction rates. CONCLUSION: The clinical impact, scientific evidence, and need for medical cost containment all advocate the discontinuation of routine usage of bacitracin in clean surgical wounds.
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