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  • Title: Cutaneous intravascular lymphoma following extravascular lymphoma of the lung.
    Author: Tomasini C, Novelli M, Ponti R, Pippione M, Bernengo MG.
    Journal: Dermatology; 2004; 208(2):158-63. PubMed ID: 15057009.
    Abstract:
    Intravascular lymphoma (IL) is a rare aggressive disease characterized by exclusive or predominant accumulation of malignant lymphoid cells within the lumina of small arteries, veins and capillaries. We describe a 74-year-old woman with IL presenting in the skin as asymptomatic teleangiectatic plaques on the thighs. The cutaneous neoplasm developed 18 months after an extravascular large B cell lymphoma of the lung and heralded its relapse. No neurologic symptoms were present during the course of the fatal disease. Immunophenotypic and immunogenotypic studies confirmed a unique B cell subtype. This case of IL is unusual for the association with an extravascular B cell lymphoma suggesting a link between the two diseases.
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