These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: High-level resistance to ethidium bromide and antiseptics in Staphylococcus aureus.
    Author: Sasatsu M, Shibata Y, Noguchi N, Kono M.
    Journal: FEMS Microbiol Lett; 1992 Jun 01; 72(2):109-13. PubMed ID: 1505735.
    Abstract:
    A gene encoding high-level resistance to ethidium bromide (EB) and antiseptics was isolated from a transferable plasmid, pTZ22, in Staphylococcus aureus. DNA sequencing revealed that the plasmid has two copies of the ebr gene that normally mediates low-level resistance to EB and antiseptics. The efflux rate for EB of strains with duplicated ebr genes was twice the rate of strains with a single ebr gene. It was concluded that the duplication of ebr is responsible for the high-level resistance to EB and antiseptics.
    [Abstract] [Full Text] [Related] [New Search]