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  • Title: Immunogenicity of Trichophyton mentagrophytes isolated from arctic foxes with ringworm.
    Author: Kostro K.
    Journal: Pol J Vet Sci; 2004; 7(1):15-20. PubMed ID: 15061480.
    Abstract:
    Immunogenicity of six strains of Trichophyton mentagrophytes var. granulosum isolated from arctic foxes with ringworm was evaluated in guinea pigs and foxes. Two strains of T. mentagrophytes (Tm-3 and Tm-4) out of six examined (Tm-1, Tm-2, Tm-3, Tm-4, Tm-5 and Tm-6) induced in the experimental foxes a strong cellular immune response measured by the leukocyte migration inhibition test (LMIT), lymphocyte transformation test (LTT), and by skin delayed-type hypersensitivity (DTH). The guinea pigs immunised with Tm-3 and Tm-4 were well protected against the artificial infection with the virulent strain of T. mentagrophytes (Tm-9). These two strains of T. mentagrophytes with high immunogenic properties were used for production of a vaccine against ringworm in foxes.
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