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  • Title: Serum enzymes associated with cholestasis.
    Author: Sotil EU, Jensen DM.
    Journal: Clin Liver Dis; 2004 Feb; 8(1):41-54, vi. PubMed ID: 15062192.
    Abstract:
    Alkaline phosphatase, gamma-glutamyl transferase, and 5' nucleotidase are the most common enzymes used in the evaluation of cholestasis. The present knowledge of these enzymes including their function, activity measurement, biologic variables of enzyme activity in healthy persons and disease states, and clinical significance are reviewed. Usefulness of enzymes patterns for diagnosis of specific cholestatic disorders and future directions in evaluation of cholestasis are also discussed.
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