These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Smoking habits in patient's who have been treated for an oral cancer: validation of self-report using saliva cotinine.
    Author: Sandhu S, Humphris G, Whitley S, Cardozo A, Sandhu A.
    Journal: Oral Oncol; 2004 Jul; 40(6):576-8. PubMed ID: 15063384.
    Abstract:
    There is a perception amongst health care professional that patients under-report their smoking habits. The aim of this study was to validate self-reported smoking habits in patients who have been treated for an oral cancer using saliva cotinine. In a cross-sectional study100 consecutive patients attending a maxillofacial oncology clinic completed a smoking related questionnaire following which a saliva sample was obtained. Saliva cotinine levels were determined by gas-liquid chromatography. The mean (SD) age 61 (11), 74% male, 26% female. The majority (79%) had Stage I/II disease, which were treated by surgery (49%), radiotherapy (14%) or combined therapy (37%). Average time (SD) since diagnosis was 28 (24) months. 42% were self-reported smokers. Cotinine assessment was possible from 91 patients. Of these 43% (39/91) were smokers by self-report, all were biochemically smokers (cotinine level>14 microg/l). 9.6% (5/52) patients who claimed to be non-smokers by self-report had cotinine levels suggesting recent active smoking. The level of agreement was excellent (kappa = 0.89), and specificity and sensitivity high (1 and 0.90, respectively). Self-reported smoking habits are reasonably accurate in this group of patients. We believe that smoking related research using self-report alone can reliably be carried out in this particular patient group.
    [Abstract] [Full Text] [Related] [New Search]