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  • Title: Screening of colonic tumors by air-inflated magnetic resonance (MR) colonography.
    Author: Lam WW, Leung WK, Wu JK, So NM, Sung JJ.
    Journal: J Magn Reson Imaging; 2004 Apr; 19(4):447-52. PubMed ID: 15065168.
    Abstract:
    PURPOSE: To assess the accuracy of air-inflated magnetic resonance (MR) colonography for the detection of colonic lesions. MATERIALS AND METHODS: A total of 36 patients underwent both colonoscopy and air-inflated MR colonography. Breath-hold sequences (volumetric interpolated breath-hold examination (VIBE) coronal, and half-Fourier acquisition single-shot turbo spin-echo (HASTE) axial and coronal, both supine and prone) were performed with a 1.5T scanner. The detection of colonic lesions by MR colonography was then correlated with the findings from the colonoscopy performed on the same day. RESULTS: Two patients were unable to complete the MR colonography examination. Analysis was based on the results from 34 patients (17 males and 17 females, 38-70 years old, mean age = 54.9 years) who completed both examinations. MR colonography depicted two of two colonic tumors, one of one P4 (> 2 cm) polyp, one of two P2 (0.5-1 cm) polyps, and two of 11 P1 (< 0.5 cm) polyps. False-positive MR colonography interpretations were noted for one P1 polyp and two P2 polyps. The overall sensitivity, positive predictive value, and accuracy of MR colonography were 38%, 67%, and 46.2%, respectively. For the detection of endoluminal lesions > 5 mm, air-inflated MR colonography yielded a sensitivity of 75%, specificity of 93.3%, accuracy of 91.2%, positive predictive value of 60%, and negative predictive value of 96.6%. CONCLUSION: Air-inflated MR colonography is a new technique that deserves further investigation.
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