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  • Title: Biosynthesis and uptake of siderophores is controlled by the PacC-mediated ambient-pH Regulatory system in Aspergillus nidulans.
    Author: Eisendle M, Oberegger H, Buttinger R, Illmer P, Haas H.
    Journal: Eukaryot Cell; 2004 Apr; 3(2):561-3. PubMed ID: 15075286.
    Abstract:
    Biosynthesis and uptake of siderophores in Aspergillus nidulans are regulated not only by iron availability but also by ambient pH: expression of this high-affinity iron uptake system is elevated by an increase in the ambient pH. Mediation of this regulation by the transcriptional regulator PacC has been confirmed via acidity- and alkalinity-mimicking mutants.
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