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  • Title: [Prospective course of therapy arresting attacks of atrial fibrillation in patients with preexcitation syndromes].
    Author: Fomina IG, Iankin VV.
    Journal: Klin Med (Mosk); 1992 Feb; 70(2):37-40. PubMed ID: 1507816.
    Abstract:
    A comparative study of antiarrhythmic drugs was performed in 81 patients with atrial fibrillation attacks in the presence of preexcitation syndrome. The first intravenous administration of cordarone was effective in 84.06%, disopyramide--in 69%, ajmaline in 44.8, verapamil in 42.1, novocaine amide in 39.4 and ethacizin in 38.5% of the patients. The first oral administration of quinidine and kinilentin arrested 80.4% of arrhythmia attacks, disopyramide 66.7% propranolol and mexitil 37.5 and 33.3%, respectively. Prospective evolution of antiarrhythmic therapy manifested with decreased therapeutic efficacy of the drugs from 55.7 to 26.2% in the whole group during the period of 1-5 years.
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