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  • Title: Potentiometric titrations in a poly(dimethylsiloxane)-based microfluidic device.
    Author: Ferrigno R, Lee JN, Jiang X, Whitesides GM.
    Journal: Anal Chem; 2004 Apr 15; 76(8):2273-80. PubMed ID: 15080738.
    Abstract:
    This paper describes a microfluidic device, fabricated in poly(dimethylsiloxane), that is used for potentiometric titrations. This system generates step gradients of redox potentials in a series of microchannels. These potentials are probed by microelectrodes that are integrated into the chip; the measured potentials were used to produce a titration curve from which the end point of a reaction was measured.
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