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  • Title: Experimental Mycoplasma hominis infection of the genital tract in BALB/c mice.
    Author: Shkarupeta MM, Lazarev VN, Govorun VM.
    Journal: Bull Exp Biol Med; 2004 Jan; 137(1):53-5. PubMed ID: 15085246.
    Abstract:
    We studied the ability of laboratory and clinical strains of Mycoplasma hominis to colonize the genital tract mucosa in BALB/c mice. Colonization with mycoplasma occurred only in mice receiving estrogen. Mycoplasma hominis strains obtained after 3-fold passage through the vaginal mucosa in mice and administered intravaginally in a dose of 0.5 x 10(8) CFU/ml caused infection in 100% animals. Inflammation in the lower genital tract was reduced by the 8th week after infection.
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