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  • Title: A method using fibrin-fixed Blue Dextran for determining the plasmin and plasmin inhibitor activities in human plasma.
    Author: Tamura Y, Otsuka A, Sone K, Sakurai E, Mori H, Sumi H, Kosugi T, Fujii S.
    Journal: Biochim Biophys Acta; 1978 Jul 07; 525(1):194-9. PubMed ID: 150858.
    Abstract:
    The fibrinolytic activity of plasmin was determined by incubating with fibrin-fixed Blue Dextran as a substrate, the Blue Dextran released being proportional to the plasmin activity. The applicability of this method for rapid and accurate evaluation of fibrinolytic activity was demonstrated by dose-response curves with purified plasmin, plasmin generated by urokinase in human plasma and euglobulin. The method can also be used to determined plasmin inhibitors in plasma.
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