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  • Title: Microlithiasis: an important cause of "idiopathic" acute pancreatitis?
    Author: Venneman NG, van Brummelen SE, van Berge-Henegouwen GP, van Erpecum KJ.
    Journal: Ann Hepatol; 2003; 2(1):30-5. PubMed ID: 15094703.
    Abstract:
    Microlithiasis is the underlying cause in a significant proportion of patients with "idiopathic" acute pancreatitis. The mechanism appears to be a relative deficiency of phosphatidylcholine in bile, with fast and extensive cholesterol crystallization as a result. Diagnosis of microlithiasis by microscopic detection of cholesterol crystals in bile is important and should lead to appropriate therapy (cholecystectomy, endoscopic sphincterotomy or ursodeoxycholic acid maintenance therapy).
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