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  • Title: [Changes in the mucosal pattern of the colon in the early stages of ulcerative and granulomatous colitis (author's transl)].
    Author: Persigehl M, Spieth W, Klose KC, Cen M.
    Journal: Rofo; 1978 Aug; 129(2):177-80. PubMed ID: 151009.
    Abstract:
    By paying attention to the detailed relief pattern of the colonic mucosa on double contrast films, it is possible to recognise the early changes due to inflammatory colonic disease. The presence of a granular appearance suggests an early stage of ulcerative colitis; multiple small flecks of contrast, sometimes surrounded by a clear area, indicate aphthous ulcers in an early stage of Crohn's disease.
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