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  • Title: The urine protein heat coagulation test--a useful screening test for proteinuria in pregnancy in developing countries: a method validation study.
    Author: Dissanayake VH, Morgan L, Broughton Pipkin F, Vathanan V, Premaratne S, Jayasekara RW, Seneviratne HR.
    Journal: BJOG; 2004 May; 111(5):491-4. PubMed ID: 15104616.
    Abstract:
    In many parts of the developing world, the urine protein heat coagulation test is routinely used to screen for proteinuria in pregnancy. The aim of this study was to determine whether > or =1+ on a standardised heat coagulation test reliably detects significant proteinuria and to compare it with the dipstick test for urinary protein. Heat coagulation test, dipstick test and 24-hour urine protein excretion results of 102 women were compared. > or =1+ on heat coagulation test is as sensitive and specific as > or =2+ on the dipstick test in detecting proteinuria of > or =500 mg/day. The heat coagulation test, however, is less sensitive than > or =1+ on dipstick in detecting lesser degrees of proteinuria.
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