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  • Title: A novel synthesis of amino-1,2-oxazinones as a versatile synthon for beta-amino acid derivatives.
    Author: Miyata O, Namba M, Ueda M, Naito T.
    Journal: Org Biomol Chem; 2004 May 07; 2(9):1274-6. PubMed ID: 15105915.
    Abstract:
    The radical addition-cyclisation of alpha, beta-unsaturated hydroxamates containing an oxime ether provides a novel method for the stereoselective synthesis of amino-1,2-oxazinones. Its synthetic utility is demonstrated by a stereoselective synthesis of beta-amino acid derivatives, such as alpha-alkyl-beta-amino-gamma-lactone and alpha,beta-disubstituted beta-lactam.
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