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  • Title: [A case of advanced gastric cancer effectively treated by combined chemotherapy of paclitaxel (TXL) and CDDP].
    Author: Nagata N, Inoue Y, Fukushima M, Shibao K, Tsurudome Y, Higure A, Hirata K, Nakayama Y, Okamoto K, Konishi T, Itoh H.
    Journal: Gan To Kagaku Ryoho; 2004 Apr; 31(4):585-8. PubMed ID: 15114704.
    Abstract:
    The patient was a 73-year-old man with unresectable advanced gastric cancer and celiac and supraclavicular lymph node metastases. Neoadjuvant chemotherapy consisting of paclitaxel (TXL) and CDDP was administered. TXL (80 mg/m2) and CDDP (25 mg/m2) was administered weekly on day 1, 8 and 15 as 1 cycle. After 4 cycles of TXL/CDDP administration, the lymph node metastases and gastric tumor had decreased almost completely in size and distal partial gastrectomy was performed. After surgery, the patient was treated with 4 courses of TXL/CDDP and has survived without recurrence to the present. TXL/CDDP is associated with few adverse events in hospital visits, and is thought to be an effective chemotherapy against advanced gastric cancer.
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