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  • Title: [Organ-saving treatment of penile cancer].
    Author: Matveev VB, Khalaf'ian EA, Volkova MI, Gurariĭ LL, Romanov VA.
    Journal: Urologiia; 2004; (2):26-30. PubMed ID: 15114748.
    Abstract:
    Conservative penis-salvage treatment provides a complete local effect in 55% cases, preservation of the penis in 51.4% patients without a fall in long-term specific and recurrence-free survival compared to penectomy and can be recommended as an alternative to penis amputation in patients with stages Tis-T2. Removal of a penile tumor raises efficacy of salvage treatment and insignificantly increases survival. Application of surgical treatment only is associated with a high rate of local recurrences. Chemoradiotherapy in penile cancer is significantly more effective vs each method alone. Radiation in a total focal dose more than 60 Gy improves local control over the tumor. Most effective are schemes of chemotherapy based on bleomycin. Polychemotherapy has no advantages over monochemotherapy with bleomycine.
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