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  • Title: Breakthrough neurological manifestation during appropriate antituberculous therapy of miliary tuberculosis.
    Author: Lolekha R, Chokephaibulkit K, Vanprapar N, Phongsamart W, Chearskul S.
    Journal: Southeast Asian J Trop Med Public Health; 2003 Sep; 34(3):634-5. PubMed ID: 15115142.
    Abstract:
    We report a 20-month-old girl with miliary pulmonary tuberculosis and normal neurological findings. While on treatment with isoniazid, rifampicin, pyrazinamide, and ethambutol for 1 month, she developed weakness of the lower extremities without meningism or altered consciousness. A computerized tomogram revealed tuberculomas and basal arachnoiditis. The cerebrospinal fluid findings were compatible with tuberculous meningitis. She responded well to systemic corticosteroids.
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