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  • Title: Simulation of compartmental models for kinetic data from a positron emission tomograph.
    Author: Coxson PG, Salmeron EM, Huesman RH, Mazoyer BM.
    Journal: Comput Methods Programs Biomed; 1992 Apr; 37(3):205-14. PubMed ID: 1511605.
    Abstract:
    Linear compartmental models are used to describe the disposition of radio-labelled compounds in regions of interest in the mammalian body, based on a time sequence of measurements from a positron emission tomograph (PET). In this paper we show how closed form solutions for the model equations have been incorporated into a computer program for simulation and parameter estimation. A typical PET data example is included to illustrate the implementation and compare the closed form method with a numerical ode solution method.
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