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  • Title: Acute myeloid leukemia presenting as bilateral proptosis from diffuse extraocular muscle infiltration.
    Author: Chen E, Morrison DG, Donahue SP.
    Journal: Am J Ophthalmol; 2004 May; 137(5):948-50. PubMed ID: 15126169.
    Abstract:
    PURPOSE: To report a case of acute myeloid leukemia with bilateral proptosis as the sole presenting sign. DESIGN: Observational case report. METHODS: A patient with bilateral proptosis was seen in consultation by pediatric ophthalmology. RESULTS: Complete blood count, computerized tomography, and bone marrow biopsy confirmed the diagnosis of acute myeloid leukemia, with the proptosis due to diffuse infiltration of all extraocular muscles. CONCLUSION: In a child with the sudden onset of proptosis without any other systemic findings, the diagnosis of acute leukemia must be considered.
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