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  • Title: Human papillomavirus type 16 viral load is higher in human immunodeficiency virus-seropositive women with high-grade squamous intraepithelial lesions than in those with normal cytology smears.
    Author: Lefevre J, Hankins C, Money D, Rachlis A, Pourreaux K, Coutlée F, Canadian Women's HIV Study Group.
    Journal: J Clin Microbiol; 2004 May; 42(5):2212-5. PubMed ID: 15131192.
    Abstract:
    Human papillomavirus type 16 (HPV-16) viral load in cervicovaginal lavage samples collected from 66 human immunodeficiency virus-seropositive women was inversely correlated with blood CD4 count (P = 0.002). HPV-16 viral load was 81-fold higher in women with cervical smears suggestive of high-grade lesions (median, 4,425,883 copies/ micro g of DNA) than in women with normal smears (median, 54,576), controlling for age (P = 0.006).
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