These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Treatment and prevention of cerebrospinal fluid leakage after craniofacial surgery for tumors involving the skull base].
    Author: Wang YQ, Ding MX, Guo ZL, Wang BY, Wu YQ.
    Journal: Shanghai Kou Qiang Yi Xue; 2004 Apr; 13(2):87-90. PubMed ID: 15133545.
    Abstract:
    PURPOSE: To evaluate the treatment and prevention of cerebrospinal fluid (CSF) leakage following removal of the skull base tumors with craniofacial approach. METHODS: A retrospective review was undertaken to analyze the clinical data of 14 cases suffering from CSF leakage after craniofacial surgery for tumors involving the cranial base. RESULTS: Ten (71.4%) case cured between 3 days and 32 days by conservative treatment including lumbar drainage. Three of four patients who needed operation had no CSF leakage after first attempt. One discontinuous leakage was closed after a second attempt. Among all cases,five(35.7%) patients developed meningitis,and one case died because of serious intracranial infection and respiration failure. CONCLUSION: Continuous lumbar cerebrospinal fluid drainage is a safe and effective treatment of CSF leakage following craniofacial surgery. However,If conservative treatment fails to arrest CSF leakage,surgical therapy is recommend with multilayer reconstruction for dural defect so as to avoid meningitis. The vital procedure for prevention of CSF leakage is watertight seal of dura mater, reconstruction of bone defect and obliteration of dead space after craniofacial surgery.
    [Abstract] [Full Text] [Related] [New Search]