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  • Title: [Analysis on therapeutic effect of Western and Chinese drug in treating intrahepatic cholestasis pregnancy].
    Author: Huang JY, Liu H.
    Journal: Zhongguo Zhong Xi Yi Jie He Za Zhi; 2004 Apr; 24(4):309-11. PubMed ID: 15143715.
    Abstract:
    OBJECTIVE: To evaluate the therapeutic effect of Yinchenghao decoction (YCHD) and S-adenosy-L-methionine (SAM) in treating intrahepatic cholestasis of pregnancy (ICP) and improving prognosis of perinatal newborn babies. METHODS: Sixty in-patients of ICP were randomly divided into two groups, the group A treated with YCHD and the group B treated with SAM. The symptom of itching and serum biochemical indexes, including glycocholic acid, bilirubin and transaminase, were observed after 3 weeks treatment, and the prognosis of perinatal newborn babies between the two groups was compared after delivery. RESULTS: After treatment, the symptom of itching, serum levels of glycocholic acid, bilirubin and transaminase improved significantly (P < 0.05) in both groups, and the prognosis of newborn in the two groups was similar (P > 0.05). CONCLUSION: Both YCHD and SAM could effectively treat ICP. The former is rather cheaper, so it is more feasible for spreading.
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