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  • Title: Impact of tobacco smoking on platelet function in apheresis products in vitro.
    Author: Scheinichen D, Heuft HG, Renken C, Jüttner B, Jaeger K, Schürholz T, Blasczyk R, Piepenbrock S, Elsner HA.
    Journal: Vox Sang; 2004 May; 86(4):252-6. PubMed ID: 15144530.
    Abstract:
    BACKGROUND AND OBJECTIVES: The aim of this study was to analyse the platelet function, over a 5-day time-period, of apheresis-derived platelet concentrates obtained from smokers and non-smokers. MATERIALS AND METHODS: Smoker and non-smoker plateletpheresis products were investigated on days 1, 3 and 5 of storage. Receptor expression (as evaluated by flow cytometry) and the platelet aggregation response were measured. RESULTS: There was only a slight loss of platelet function in apheresis products from smokers compared to non-smokers. CONCLUSIONS: Smoking does not significantly change the quality of platelet preparations. The current practice, of not to exclude smokers from platelet donation, can be continued.
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