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  • Title: Clinical manifestation of aldosteronoma.
    Author: Al Fehaily M, Duh QY.
    Journal: Surg Clin North Am; 2004 Jun; 84(3):887-905. PubMed ID: 15145241.
    Abstract:
    Formerly, fewer than 1% of patients with hypertension were believed to have primary hyperaldosteronism; however, recent studies have suggested a higher prevalence, in 5% to 10% of patients with hypertension. Hypokalemia is not necessary for the diagnosis and is probably a sign of more advanced disease. The best diagnostic test is the plasma aldosterone concentration to plasma renin activity (PAC/PRA) ratio. Excess aldosterone level has a deleterious effect on the cardiovascular system. Aldosteronomas should be differentiated from idiopathic hyperaldosteronism (IHA),because they are curable by laparoscopic adrenalectomy.
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