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  • Title: Impaired response rates, but satisfying protection rates to influenza vaccination in dialysis patients.
    Author: Vogtländer NP, Brown A, Valentijn RM, Rimmelzwaan GF, Osterhaus AD.
    Journal: Vaccine; 2004 Jun 02; 22(17-18):2199-201. PubMed ID: 15149777.
    Abstract:
    Dialysis patients show impaired responses to several vaccines. Limited recent data are available on influenza vaccination in these patients. In the 1998-1999 influenza season, 44 dialysis patients received a standard trivalent vaccination followed by a booster two months later. The serum antibody responses in these patients were compared with those found in healthy subjects. A fourfold rise in serum hemagglutination inhibition titre was achieved in 23-58% of all patients. Protective titres were reached in 53-93% of the patients. Since protective antibody titers can be induced, it is recommended to vaccinate dialysis patients annually against influenza.
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