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  • Title: Increased susceptibility of beta7-integrin-deficient neonatal mice in the early stage of Cryptosporidium parvum infection.
    Author: Mancassola R, Lacroix-Lamandé S, Barrier M, Naciri M, Salmon H, Laurent F.
    Journal: Infect Immun; 2004 Jun; 72(6):3634-7. PubMed ID: 15155674.
    Abstract:
    Numerous inflammatory cells are recruited in response to Cryptosporidium parvum infection. These cells include interferon gamma-producing T lymphocytes, which are of major importance for the resolution of infection. Here, we show that beta7 integrin is not essential for the control of infection in mice but that beta7-deficient neonatal mice are more susceptible during the early stages of infection.
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