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  • Title: Early in-vitro histological chondral differentiation.
    Author: Gil J, Gimeno M, Murillo-Ferrol NL, Bascuas JA.
    Journal: Histol Histopathol; 1992 Apr; 7(2):169-74. PubMed ID: 1515699.
    Abstract:
    In vitro chondrogenesis is possible in the chick embryo from stage 4 of Hamburger and Hamilton (1951), only 18-19 hours of incubation, before somite formation. In stage 4 of Hamburger and Hamilton (1951) the chondroblasts are placed laterally to the primitive streak and notochord cells are not necessary for cartilage differentiation.
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