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  • Title: Circulating antigen-antibody complexes in patients with immune complex disorders and following kidney transplantation.
    Author: Hasková V, Matl I, Kaslík J, Kocandrle V.
    Journal: Czech Med; 1978; 1(2):111-5. PubMed ID: 151619.
    Abstract:
    The presence of circulating soluble complexes antigen-antibody was investigated by means of our simple test (1) in small serum samples of patients before and after kidney transplantation. We found a higher incidence of positive test results in patients with an original diagnosis of chronic glomeruleonephritis following transplantation in 37.1%, than before transplantation (in 28.5%). In both instances, however circulating immune complexes were less frequent than in a previously studied group of patients with chronic glomerulonephritis (66.6%), or particularly in glomerulonephritis cases with the characteristics of disease activity (100%) positivity. In patients suffering from pyelonephritis, a diseases not due to immune complexes, 18% of sera were positive. After transplantation the number of positive sera rose to 35.5% in 13 patients. The reasons for this finding are being analysed.
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