These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Immunoassays and sequence-specific DNA detection on a microchip using enzyme amplified electrochemical detection.
    Author: Dill K, Montgomery DD, Ghindilis AL, Schwarzkopf KR.
    Journal: J Biochem Biophys Methods; 2004 May 31; 59(2):181-7. PubMed ID: 15163529.
    Abstract:
    A CMOS fabricated silicon microchip was used as a platform for immunoassays and DNA synthesis and hybridization. The chip is covered with a biofriendly matrix wherein the chemistries occur. The active silicon chip has over 1000 active electrodes that can be individually addressed for both synthesis of DNA and protein attachment to a membrane on the chip surface. Additionally, the active chip can be further used for the detection of various analytes at the chip surface via digital read out resulting from the redox enzymes on the captured oligonucleotide or antibody.
    [Abstract] [Full Text] [Related] [New Search]