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  • Title: Fatal cytophagic histiocytic panniculitis.
    Author: Seçmeer G, Sakalli H, Gök F, Ozen S, Kara A, Cengiz AB, Ceyhan M, Gürgey A, Gögüs S, Kanra G.
    Journal: Pediatr Dermatol; 2004; 21(3):246-9. PubMed ID: 15165205.
    Abstract:
    Individual cases of so-called Weber-Christian disease with a bleeding diathesis have been reported for several years. These were originally diagnosed as Weber-Christian disease, but have been recategorized on review as a chronic, visceral, and cutaneous histiocytic (cytophagic) panniculitis, progressing to liver dysfunction and jaundice and a terminal hemorrhagic diathesis. We report here a rare catastrophic form of systemic panniculitis in an adolescent girl. Despite compelling clinical evidence, the diagnosis was made only on postmortem biopsies.
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