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  • Title: Splenic marginal zone B-cell lymphoma associated with primary Sjögren's syndrome.
    Author: Nishiyama S, Miyawaki S.
    Journal: Clin Rheumatol; 2004 Jun; 23(3):242-5. PubMed ID: 15168154.
    Abstract:
    We describe a 67-year-old woman with primary Sjögren's syndrome who developed a splenic marginal zone B-cell lymphoma, and complained of a dry mouth and Raynaud's phenomenon. She had splenomegaly, swollen lymph nodes and monoclonal IgM-kappa cryoglobulin. After splenectomy, Raynaud's phenomenon had improved with the decrease of cryoglobulin. This is the first case of primary Sjögren's syndrome with splenic marginal zone B-cell lymphoma to be reported.
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