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  • Title: Fusion has found its calcium sensor.
    Author: Meldolesi J, Chieregatti E.
    Journal: Nat Cell Biol; 2004 Jun; 6(6):476-8. PubMed ID: 15170455.
    Abstract:
    Synaptic vesicle exocytosis, a finely tuned process that results in rapid neurotransmitter release, is still not fully understood. Studies in a simple reconstituted lipid bilayer system have now definitively demonstrated that synaptotagmin has a key role in calcium-mediated exocytosis and have also revealed additional aspects of exocytic fusion.
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