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  • Title: Synthesis and evaluation of polyhydroxylated near-infrared carbocyanine molecular probes.
    Author: Zhang Z, Achilefu S.
    Journal: Org Lett; 2004 Jun 10; 6(12):2067-70. PubMed ID: 15176820.
    Abstract:
    [reaction: see text] A new near-infrared (NIR) fluorescent molecular probe derived from indocarbocyanine dye and galactose was prepared, and the procedure was optimized. The presence of a nonionic polyhydroxyl moiety between hydrophobic groups enhances solubility and possibly minimizes aggregation in aqueous solutions. The structural framework of this molecule provides multivalent sites for labeling diverse molecules.
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