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  • Title: Metastatic neuroblastoma presenting with binocular blindness from intracranial compression of the optic nerves.
    Author: Lau JJ, Trobe JD, Ruiz RE, Cho RW, Wechsler DS, Shah GV, Gebarski SS.
    Journal: J Neuroophthalmol; 2004 Jun; 24(2):119-24. PubMed ID: 15179064.
    Abstract:
    A 2-year-old boy with blindness as an isolated symptom was found to have no light perception binocularly because of compression of both optic nerves by a neuroblastoma infiltrating the walls of the optic canals and medial sphenoid bone. Imaging disclosed a primary tumor near the kidney and multiple osseous metastases. Although neuroblastoma commonly causes blindness by metastasis to the orbit, it rarely causes bilateral blindness from intracranial compression of the optic nerves. This is the first report of bilateral blindness as the presenting feature.
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