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  • Title: Libraries from natural product-like scaffolds.
    Author: Boldi AM.
    Journal: Curr Opin Chem Biol; 2004 Jun; 8(3):281-6. PubMed ID: 15183326.
    Abstract:
    Natural products are an attractive source of varied structures that exhibit potent biological activities, and desirable pharmacological profiles. Since the relatively recent advent of high-throughput organic synthesis in the drug discovery process, several design approaches have been applied to the construction of screening libraries. Libraries of natural-product derivatives, natural-product-like compounds prepared by total synthesis, and libraries derived from natural-products are several types that have been reported.
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