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  • Title: A circadian clock regulates the process of ERG b- and d-wave dominance transition in dark-adapted zebrafish.
    Author: Ren JQ, Li L.
    Journal: Vision Res; 2004; 44(18):2147-52. PubMed ID: 15183681.
    Abstract:
    In zebrafish, during dark adaptation following bright light adaptation, the dominance of electroretinogram (ERG) b- and d-waves switches. In the early dark adaptation, when visual sensitivity is cone-dominant, both the b- and d-waves are readily recorded. In the late dark adaptation, along with the increase of rod sensitivity, the b-wave becomes dominant whereas the d-wave is gradually lost. The time for the ERG b- and d-wave dominance transition varies between the day and night. The transition requires a longer amount of time in the night and early morning than in the afternoon. This pattern of timing for ERG b- and d-wave dominance transition persists in constant light and can be reversed after exposure to a reversed light-dark cycle. The data suggest that the transition of the dominance of ERG b- and d-waves is regulated by an endogenous circadian clock.
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