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  • Title: Spiradenocarcinoma of the breast arising in a long-standing spiradenoma.
    Author: Ribeiro-Silva A, Shaletich C, Careta RS, Kazava DK, Siqueira MC, Ponton F.
    Journal: Ann Diagn Pathol; 2004 Jun; 8(3):162-6. PubMed ID: 15185264.
    Abstract:
    The embryologic origin of the breast is related to salivary and sweats glands. Thus, breast neoplasms may show differentiation toward these tissues, although this is a rare event in humans. We report the clinicopathologic and immunohistochemical features of a 57-year-old woman presenting with a spiradenoma that originated in breast tissue and became malignant 40 years later. Some histogenetic concepts relevant to this case are discussed, along with a brief review of this neoplasm.
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