These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Factors contributing to thixotropy of inspiratory muscles.
    Author: Izumizaki M, Shibata M, Homma I.
    Journal: Respir Physiol Neurobiol; 2004 Jun 25; 140(3):257-64. PubMed ID: 15186787.
    Abstract:
    Thixotropy is a passive property of the skeletal muscle dependent on the muscle's immediate history of contraction and length change. Thixotropic properties of inspiratory muscles, introduced by forceful muscle contraction at an inflated lung volume, cause an increased end-expiratory position (EEP) of the rib cage. We searched for factors contributing to the development of inspiratory muscle thixotropy in nine healthy subjects. Using induction plethysmography, we examined aftereffects on EEP of the duration of inspiratory muscle contraction and subsequent muscle relaxation. We also studied effects of inspiratory effort intensity measured by mouth pressure at different lung volumes. EEP elevation was noted subsequent to 5-s contraction followed by 2-s relaxation and was enhanced when conditioned at higher lung volumes with a strong inspiratory effort. Our results suggest four factors that influence inspiratory muscle thixotropy: (1) intensity of muscle contraction, (2) lung volume when contraction occurs, (3) duration of contraction, and (4) muscle relaxation.
    [Abstract] [Full Text] [Related] [New Search]