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  • Title: Synthesis of isothiazole derivatives with potential biological activity.
    Author: Burak K, Machoń Z.
    Journal: Pharmazie; 1992 Jul; 47(7):492-5. PubMed ID: 1518893.
    Abstract:
    The synthesis of acyl and ureido derivatives of substituted amides of 3-methyl-5-aminoisothiazole-4-carboxylic acid is presented. The structures of the compounds obtained were established on the basis of IR, 1H NMR and elemental analysis. The influence on the circulatory system of the derivatives was investigated. All structures of the compounds obtained were fully confirmed by IR and 1H NMR as well as by elemental analysis (Table).
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