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  • Title: [Ventricular late potentials--methods and clinical importance].
    Author: Breithardt G, Fetsch T, Reinhardt L, Shenasa M, Borggrefe M.
    Journal: Ther Umsch; 1992 Aug; 49(8):550-8. PubMed ID: 1519184.
    Abstract:
    Ventricular late potentials are due to regionally depressed inhomogenous conduction, mainly in the border zone of a previous myocardial infarction. They can be recorded noninvasively using high-resolution signal-averaging techniques. They are almost never detectable in normals, whereas they represent a frequent finding in postmyocardial infarction patients. The presence of ventricular late potentials after previous myocardial infarction predicts the subsequent occurrence of hemodynamically severe sustained ventricular tachycardia and/or sudden cardiac death. Their predictive significance can be increased by combining signal-averaging with long-term ECG recording and estimates of left-ventricular ejection fraction. However, despite recent major improvements in identification of patients at risk, there is still a need for an effective mode of prevention of serious ventricular tachyarrhythmias after myocardial infarction.
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