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  • Title: Diarrhoeic shellfish toxins in Adriatic Sea mussels evaluated by an ELISA method.
    Author: Tubaro A, Sosa S, Bruno M, Gucci PM, Volterra L, Della Loggia R.
    Journal: Toxicon; 1992; 30(5-6):673-6. PubMed ID: 1519256.
    Abstract:
    A competitive enzyme immunoassay (ELISA) was used to determine the presence of okadaic acid (OA) and/or dinophysistoxin-1 (DTX-1) in mussels. The accuracy and sensitivity of the ELISA method has been checked. The sensitivity of the method (100 ng/g of hepatopancreas) makes it possible to determine OA concentrations ten times lower than the tolerance limits established by the Health Authorities of many countries. For the first time, OA and/or DTX-1 were detected in mussels (Mytilus galloprovincialis) collected in different stations along the Adriatic Sea coasts.
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