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  • Title: The early migration of Elaphostrongylus rangiferi in goats.
    Author: Handeland K, Skorping A.
    Journal: Zentralbl Veterinarmed B; 1992 Jun; 39(4):263-72. PubMed ID: 1519406.
    Abstract:
    The migration of nematodes of the genus Elaphostrongylus (Metastrongyloidea: Protostrongylidae) from the gut into the tissues of ruminants has not been described. Detailed histologic studies were performed on five goat kids that had received oral doses of 1,000-1,500 infective larvae of Elaphostrongylus rangiferi Mitskevich, 1960 and were subsequently autopsied at days 2, 4, 6, 10, and 14 post inoculation. The main migratory route of E. rangiferi larvae seemed to be haematogenous. The larvae penetrated the venules of the abomasum and followed the blood stream via the liver to the lungs. In the lungs, the larvae entered pulmonary venules and passed into the arterial circulation reaching the central nervous system (CNS) and other organs between days 6 and 10 post inoculation. Some of the larvae that had lodged in tissues outside the CNS probably migrated into it along the spinal nerves. A marked eosinophilia was present from day 8 post inoculation.
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