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  • Title: Early events in glutamate receptor trafficking.
    Author: Vandenberghe W, Bredt DS.
    Journal: Curr Opin Cell Biol; 2004 Apr; 16(2):134-9. PubMed ID: 15196555.
    Abstract:
    Glutamate receptors are the primary mediators of excitatory synaptic transmission in the mammalian central nervous system. Activity-dependent changes in the number of postsynaptic glutamate receptors underlie aspects of synaptic plasticity and provide a mechanism for information storage in the brain. Recent work shows that receptor exit from the endoplasmic reticulum represents a critical regulatory step in glutamate receptor trafficking to the neuronal cell surface.
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