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  • Title: Expression of testis specific ankyrin repeat and SOCS box-containing 17 gene.
    Author: Guo JH, Saiyin H, Wei YH, Chen S, Chen L, Bi G, Ma LJ, Zhou GJ, Huang CQ, Yu L, Dai L.
    Journal: Arch Androl; 2004; 50(3):155-61. PubMed ID: 15204681.
    Abstract:
    Human ASB-17 (Ankyrin Repeat and SOCS Box-containing 17) is a recently identified gene belonging to the ASB family, isolated from testis cDNA library. Human ASB-17 is expressed exclusively in testis among 16 tissues, revealed by Northern blot. Mouse Asb-17 was shown to be expressed from the third week post birth to adult by semi-quantitative RT-PCR analysis. In situ hybridization on frozen sections demonstrated that Asb-17 is expressed in spermatogenic cells in adult mouse, but not in Leydig cell and epididymis in adult mouse. ASB-17 proteins are highly conserved in mammals including human, mouse, rat, Canis familiaris and Macaca fascicularis.
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