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Title: Medical management of diabetic retinopathy. Author: Sjølie AK, Møller F. Journal: Diabet Med; 2004 Jul; 21(7):666-72. PubMed ID: 15209756. Abstract: Although current treatment and prevention of diabetic retinopathy with laser photocoagulation, and tight metabolic and blood pressure control has reduced the risk of visual loss, there is still a need for additional therapies. A literature review on medical therapies for diabetic retinopathy has been performed, and the following classes of drugs are discussed: blockers of the renin-angiotensin system, protein kinase C-beta inhibitors, glitazones, somatostatin analogues, lipid-lowering drugs and anti-inflammatory drugs. There is experimental and clinical data suggesting beneficial effect from several classes of drugs on diabetic retinopathy, and results from large clinical trials are awaited within the next 3-4 years.[Abstract] [Full Text] [Related] [New Search]