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  • Title: Short report: High prevalence of multidrug-resistant Plasmodium falciparum malaria in the French territory of Mayotte.
    Author: Pettinelli F, Pettinelli ME, Eldin de Pécoulas P, Millet J, Michel D, Brasseur P, Druilhe P.
    Journal: Am J Trop Med Hyg; 2004 Jun; 70(6):635-7. PubMed ID: 15211004.
    Abstract:
    A drug-resistance survey was conducted in the French territory of Mayotte in the Comorian Islands in the Indian Ocean where malaria is endemic. A high prevalence of resistant Plasmodium falciparum parasites was observed, not only to chloroquine (88%) and pyrimethamine (99%), but more surprisingly to quinine (17%), mefloquine (9%), and amodiaquine (24%). This leaves few treatment alternatives other than artemisine-mefloquine combinations. However, despite notification to French Health authorities three years ago, inadequate treatment (chloroquine plus sulfadoxine-pyrimethamine) is still used in this locality. Thus, people still die of malaria in this remote territory of France.
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