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  • Title: [Contribution of maxillofacial signs in the diagnosis of Gardner syndrome].
    Author: Touré G.
    Journal: Rev Stomatol Chir Maxillofac; 2004 Jun; 105(3):177-81. PubMed ID: 15211217.
    Abstract:
    Familial adenomatous polyposis (FAP) and Gardner syndrome are mendelian dominant inherited conditions. Both diseases are linked to mutations on the long arm of chromosome 5 (5q21) referred to as the adenomatous polyposis locus. Gardner syndrome involves endodermal, mesodermal and ectodermal layers. Nondigestive and maxillofacial lesions such as osteomas, odontomas, epidermoid inclusion cysts can disclose the syndrome. Colorectal cancer is the most important factor of prognosis.
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